Coconut water is one of the world’s most versatile natural product with increasing scientific evidence that support the role of coconut water in health and medicinal application. The aim of this work is to assess the biochemical properties of coconut water using standard and accepted methods; inorganic ions, total proteins, albumin, PH, specific gravity, volume, and weight. Thirty (30) coconut samples (24 ripe and 6 unripe) were used for the study. The result shows that Nigeria coconut nut water contains various electrolytes, devoid of bicarbonates and albumins. Also result shows that both ripe and unripe coconut water contain high mean K+ concentration (Meq/L, ?±SE) of 44.75±1.02 and 35.23±3.41 respectively with a PH of 5.4. The application of coconut water in clinical trial for the treatment of pathological conditions is advocated.

Cortisone is a steroid hormone, responsible for the stress resp, released from the adrenal gland, altered activity of the hypothalamo-pituitary-adrenal (HPA) axis is one of the most consistent findings in depression. The present investigation aimed to study the serum cortisol level in patients with major depression. Serum cortisol level was higher in depression patients 14.5±3.01µg/dl than in control group 11.56±1.33 µg/dl. Conclusion: Hyper secretion of corticotrophin releasing hormone increased cortisol levels in plasma, urine and cerebrospinal fluid exaggerated cortisol responses to adrenocorticotropic hormone and enlarged pituitary and adrenal glands occurs in individuals suffering from severe mood disorders.