Abstract

Several compounds of plant origin like Ascorbic acid, ellagic acid and tannins are known to be associated with anti mutagenic activity. Mechanism of mutagenesis is complex and different in different mutagens and thus antimutagenesis process is also varied. During present investigation protective effects of. A. spinosous and A. hybridus ethanolic extracts exhibit concentration dependent effect of EMS induced toxicity against S. typhimurium. The 95% of survival S.typhimurium at concentration of 8 mg/plate of ethanolic extract of A.spinosus and A.hybridus caused 96% survival of S. typhimurium against EMS induced toxicity at 8 mg/plate concentration. Keywords: Amaranthus spinosus; Ethanolic extract; Antimutagenic assay.